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Table Of Content:
- MYC on the Path to Cancer - PMC
- Targeting oncogenic Myc as a strategy for cancer treatment | Signal ...
- MYC Activation Is a Hallmark of Cancer Initiation and Maintenance ...
- RAS and MYC: Co-conspirators in Cancer - National Cancer Institute
- Myc - Wikipedia
- Taking the Myc out of cancer: toward therapeutic strategies to ...
- c-Myc in breast cancer
- Pan-cancer Alterations of the MYC Oncogene and Its Proximal ...
- A Core MYC Gene Expression Signature Is Prominent in Basal-Like ...
- Oncogene Myc - an overview | ScienceDirect Topics
1. MYC on the Path to Cancer - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345192/
The MYC oncogene contributes to the genesis of many human cancers. Recent insights into ...
2. Targeting oncogenic Myc as a strategy for cancer treatment | Signal ...
https://www.nature.com/articles/s41392-018-0008-7
Feb 23, 2018 ... The MYC family oncogene is deregulated in >50% of human cancers, and this deregulation is frequently associated with poor prognosis and ...
3. MYC Activation Is a Hallmark of Cancer Initiation and Maintenance ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031954/The notion that cancer is a genetic disease associated with discrete and definable events that activate oncogenes and/or inactivate tumor suppressor genes ...
4. RAS and MYC: Co-conspirators in Cancer - National Cancer Institute
https://www.cancer.gov/research/key-initiatives/ras/ras-central/blog/2017/myc-ras
Jul 13, 2017 ... In cancer, the pathways that lead to the phosphorylation of MYC at S62, such as those driven by oncogenic RAS, are often upregulated, and ...
5. Myc - Wikipedia
https://en.wikipedia.org/wiki/Myc
In cancer, c-myc is often constitutively (persistently) expressed. This leads to the increased expression of many genes, some of which are involved in cell ...
6. Taking the Myc out of cancer: toward therapeutic strategies to ...
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-020-01291-6
Jan 4, 2021 ... c-Myc is a transcription factor that is constitutively and aberrantly expressed in over 70% of human cancers. Its direct inhibition has been ...
7. c-Myc in breast cancer
https://pubmed.ncbi.nlm.nih.gov/11021963/
Ever since Bishop and his co-workers discovered the c-myc gene in the late 1970s (Bishop 1982), voluminous literature has documented its central role in ...
8. Pan-cancer Alterations of the MYC Oncogene and Its Proximal ...
https://www.cell.com/fulltext/S2405-4712(18)30097-8
Mar 28, 2018 ... The MYC protein functions as a transcription factor that responds to and integrates these signals into broad changes in gene expression, ...
9. A Core MYC Gene Expression Signature Is Prominent in Basal-Like ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006693
Aug 19, 2009 ... Background The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response ...
10. Oncogene Myc - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/oncogene-myc
Myc · ) gene, are often upregulated and/or amplified in cancers and can support neoplastic transformation. · gene is located at chromosome 8q24 within the region ...
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